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Chest pain, trouble breathing or severe bleeding?Life-threatening emergency? Call 911.

Urgent care centers and walk-in clinics in Sioux Falls, SD

59urgent care centers and walk-in clinics serving Sioux Falls. 11 list 24-hour service.

Urgent care centers and walk-in clinics in Sioux Falls

Showing 1–10 of 59, sorted by distance from the city center

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  • Urgent care
  • City center (distances measured from here)

Sioux Falls urgent care at a glance

Sioux Falls has 59 urgent care centers on our listings across 8 ZIP codes. 11 list 24-hour hours, 25 list Sunday hours and 8 more stay open past 7 PM on at least one weekday. The closest to the city center is AveraNow in Hy-Vee at 10th & Cleveland, 0.6 mi away.

  • 59urgent care centers
  • 11list 24-hour hours
  • 27list Saturday hours
  • 25list Sunday hours
  • 8open past 7 PM on a weekdaynot counting 24-hour clinics
  • 35list insurance networks
Closest to the city centerAveraNow in Hy-Vee at 10th & Cleveland0.6 mi from the city center

8 ZIP codes

  • 5710815
  • 5710512
  • 571069
  • 571048
  • 571035
  • 571104
  • 571174
  • 571072

Counts come from the listings above and the hours each clinic publishes. Hours are not listed for 19 of the 59. Hours and networks change, so call to confirm.

Open late, weekends and 24 hours in Sioux Falls

Open 24 hours 11

Open on Sunday 25

Open past 7 PM on weekdays 8

From the hours each clinic lists, in the same order as the list above; the list shows which are open right now. Hours change, so call to confirm.

Insurance networks listed by Sioux Falls clinics

35 of the 59 urgent care centers here list at least one insurance network. These are the networks listed on our listings, drawn from insurer directories; call the clinic to confirm your plan before you go. A network missing here does not mean a clinic does not take it.

  • Aetna31 of 59
  • UMR27 of 59
  • UnitedHealthcare26 of 59
  • Cigna15 of 59
  • Medicare8 of 59
  • Humana1 of 59

Other clinics and medical services in Sioux Falls

5 listings that are not urgent care, such as primary care, specialists, pharmacies and hospitals. Open one for its own page.

Brian Skow, MD800 E 21st St, Sioux Falls, SD 57105Medical practiceDr. Beth E. Lapka, MD1305 W 18th St, Sioux Falls, SD 57105Medical practiceDr. Scott G. Vankeulen, MD1305 W 18th St, Sioux Falls, SD 57105Medical practiceGreene Stacia L MD6110 S Minnesota Ave # 101, Sioux Falls, SD 57108Medical practiceSheridan Jamie L MD1305 W 18th St, Sioux Falls, SD 57105Medical practice

Urgent care vs. ER vs. primary care

General information, not specific to Sioux Falls: knowing where to go saves time and money. Here's how urgent care compares to a hospital ER and a primary care physician.

Urgent care

Today, when it can’t wait

Non-life-threatening illness or injury that can't wait for an appointment.

  • Flu, UTI, ear infection
  • Sprains and stitches
  • X-ray, COVID test
  • Sports physicals
Typical cost
$100–$250 self-pay; $25–$75 copay with insurance
Wait time
Usually 15–45 minutes; many offer online check-in.
Hours
Evenings and weekends; many open 7 days, some 24 hours.
Emergency room

Now, if it could be life-threatening

Life- or limb-threatening symptoms; severe pain, bleeding, breathing problems, suspected stroke or heart attack.

  • Chest pain
  • Stroke symptoms
  • Severe trauma or burns
  • Difficulty breathing
Typical cost
$1,200–$2,500+ self-pay; $150–$500+ copay with insurance
Wait time
Hours, depending on triage. Severe cases seen first.
Hours
24/7.
Primary care

In a day or two, or ongoing

Routine care, chronic conditions, ongoing health management. Schedule in advance.

  • Annual physical
  • Diabetes and blood pressure management
  • Screenings
  • Referrals
Typical cost
$100–$200 self-pay; $20–$40 copay with insurance
Wait time
Same-day availability rare; appointments often days to weeks out.
Hours
Weekday business hours, by appointment.
Chest pain, trouble breathing or severe bleeding? Call 911.

This is general information, not medical advice. Costs are typical US ranges, not quotes from any clinic listed here.

What a visit typically costs

Without insurance

Typical ranges, not quotes
  • Urgent care$100 – $250
  • Primary care$100 – $200
  • Hospital / ER$1,200 – $2,500+
$0$1,000$2,000$3,000+

With insurance (copay)

Typical ranges, not quotes
  • Urgent care$25 – $75
  • Primary care$20 – $40
  • Hospital / ER$150 – $500+
$0$200$400$600+

When to go to urgent care, and when to call 911

Urgent care is a good fit for

  • Fever
  • Sore throat
  • Urinary tract infection
  • Sprain or strain
  • Earache
  • Work / sports / school physical
  • Laceration
  • Puncture wound
  • Migraine headache
  • Sinus infection
  • Cough
  • Rash
  • Back pain
  • Car accident
  • Elevated blood pressure
  • General wellness exam

Call 911 or go to the ER for

  • Chest pain
  • Severe abdominal pain
  • Difficulty breathing or shortness of breath
  • Sudden blurred vision
  • Numbness in face, arm, or leg, especially on one side
  • Weakness on one side of the body or difficulty speaking
  • Sudden, severe headache
  • Bleeding that won't stop
  • Coughing up or vomiting blood
  • Severe burns

Do not delay treatment for a serious medical problem.

Common reasons people visit urgent care

General information: urgent care centers handle non-emergency illness, injury and routine needs, usually the same day. Services differ from clinic to clinic, so check the listing or call ahead.

Illness

  • Cold & flu symptoms
  • Strep throat
  • Sinus infection
  • Ear infection
  • Bronchitis
  • Pneumonia (mild)

Injury

  • Sprains & strains
  • Minor fractures
  • Lacerations & cuts (stitches)
  • Puncture wounds
  • Burns (minor)
  • Animal & insect bites

Diagnostics & procedures

  • X-rays (on-site)
  • EKG / ECG
  • Lab tests & bloodwork
  • STD testing
  • Pregnancy testing
  • Drug screening

Preventive & routine

  • Sports physicals
  • School & camp physicals
  • Work / DOT physicals
  • Travel vaccinations
  • Flu shots
  • Tetanus boosters

Frequently asked questions

How many urgent care centers are in Sioux Falls, SD?

Sioux Falls, SD has 59 urgent care centers listed on UCL.

Is there a 24-hour urgent care in Sioux Falls, SD?

Yes. 11 facilities offer 24-hour service in Sioux Falls. Use the "Open 24 hours" filter on the listings above to see them.

Are urgent care centers in Sioux Falls open on weekends?

27 of the 59 urgent care centers listed in Sioux Falls list Saturday hours and 25 list Sunday hours. Hours are not listed for 19, so call those to check. Holiday hours are often shorter; confirm with the clinic before a holiday visit.

Which urgent care centers in Sioux Falls are open late?

8 centers list weekday hours past 7 PM, and 11 list 24-hour hours. They are named in the "Open late, weekends and 24 hours" lists on this page. Hours change, so call before a late visit.

Which urgent care is closest to the center of Sioux Falls?

AveraNow in Hy-Vee at 10th & Cleveland is the listed urgent care center closest to the center of Sioux Falls, about 0.6 mi away. The list above shows verified clinics first, then the rest by distance from the city center.

What insurance do urgent care centers in Sioux Falls take?

On our listings, the networks named most often by Sioux Falls urgent care centers are Aetna (31), UMR (27) and UnitedHealthcare (26), with the number of clinics in brackets. 35 of the 59 list at least one network. Call the clinic to confirm it takes your plan.

Do urgent care centers in Sioux Falls require an appointment?

Most urgent care centers accept walk-in patients without an appointment, though some offer optional online check-in. Call the clinic or check its listing to confirm its policy.

What does urgent care cost in Sioux Falls, SD?

Out-of-pocket urgent care costs in SD typically range from $100–$250 for an uninsured visit, depending on services; visits that include X-rays, lab tests, or minor procedures (stitches, splints) usually run $200–$400. With insurance, the visit cost is usually a copay of $25–$75. These are typical ranges, not quotes; verify with each facility before visiting.

When should I go to urgent care vs the ER in Sioux Falls?

Go to urgent care for non-life-threatening illness or injury: fevers, sprains, infections, minor cuts, mild asthma, UTIs, flu, rashes. Go to the ER for chest pain, severe abdominal pain, difficulty breathing, sudden weakness or numbness, severe head injury, heavy bleeding, severe burns, or any potentially life-threatening symptom. When in doubt with a serious symptom, call 911.

Do urgent care centers in Sioux Falls treat children?

Most urgent care centers treat patients of all ages, including children, and some are pediatric-only; call ahead to check a clinic's minimum age. For infants under 6 months with a high fever, contact a pediatrician or the ER directly.

Can I get an X-ray, lab test, or stitches at urgent care in Sioux Falls?

Many urgent care centers offer on-site X-rays, basic lab tests (strep, flu, COVID, mono, UTI), IV fluids, sutures, and splints, but not all do. More advanced imaging (MRI, CT) typically requires a hospital. Call the clinic to confirm before you go.

Do urgent care centers in Sioux Falls prescribe antibiotics?

Yes. Urgent care providers can prescribe antibiotics for bacterial infections (strep throat, UTIs, sinus and ear infections, skin infections) when clinically appropriate. They follow CDC stewardship guidelines, so they will not prescribe antibiotics for viral illness like the common cold or most cases of bronchitis.

Can I do a telehealth visit instead of going to urgent care in Sioux Falls?

Some urgent care centers offer telehealth visits for non-emergency issues like cold and flu symptoms, prescription refills, rashes, or follow-up care. In-person visits are still required for X-rays, lab tests, and physical exams. Ask the clinic whether it offers telehealth.

For clinic owners

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