Express Care
1008 N Main St, Sikeston, MO 63801
- Open weekdays 8 AM to 7 PM and weekends 8 AM to 4 PM
- 1 insurance network listed
- 0.9 mi from the center of Sikeston
Nearby urgent care
- Ferguson Medical Group Urgent: Livermore III George H MD
- Missouri Delta Women’s Care Center
- Barton-Jolly building
Hours
- Mon8 AMto7 PM
- Tue8 AMto7 PM
- Wed8 AMto7 PM
- Thu8 AMto7 PM
- Fri8 AMto7 PM
- Sat8 AMto4 PM
- Sun8 AMto4 PM
Hours can change on holidays; call to confirm.
Insurance
1 insurance network lists this location.
- Aetna3 plans
Plan names listed (3)
- Aetna Health Inc. - Georgia
- Aetna Health Inc. - New Jersey
- Aetna Health Inc. - PA
Call to confirm your plan. Networks change and the clinic has the final word.
About Express Care
Express Care is an urgent care center at 1008 N Main St, Sikeston, MO 63801. It is about 0.9 miles from the center of Sikeston, and the nearest other city we list is Matthews, 9.0 miles away. Its listed hours: open weekdays 8 AM to 7 PM and weekends 8 AM to 4 PM. It is listed with 1 insurance network: Aetna. It has 1 published review on this site, averaging 1.0 out of 5.
At a glance
- Care level
- Urgent care
- Open 24 hours
- No
- Days open
- 7 days a week
- Insurance networks listed
- 1
- Phone
- (573) 472-6001
- To the center of Sikeston
- 0.9 mi
- Reviews
- 1, average 1.0 of 5
If it’s an emergency
Call 911 for chest pain, trouble breathing, signs of a stroke, severe bleeding or a serious injury. Urgent care centers are not emergency rooms.
Call 911What urgent care centers usually treat
General information, not medical advice. Services vary; call Express Care to ask what it offers.
- Fever and flu
- Cuts and stitches
- Sprains and X-rays
- Sore throat and strep
- Urinary tract infections
- Rashes and allergic reactions
- Ear infections
- Vaccines and physicals
- COVID and flu tests
- Work and DOT physicals
Before you go
General checklist.
- A photo ID
- Your insurance card, if you have one
- A list of your medicines and allergies
- A way to pay a copay or the visit
- Call (573) 472-6001 to confirm today’s hours and that your plan is accepted
- Most urgent care centers take walk-ins, and some also offer online check-in; ask when you call
Cost at a glance
Typical US ranges, not quotes. Ask Express Care for its prices when you call.
- Urgent care visit, billed before insurance$229–$445
- Urgent care copay with insurance$25–$75
- Emergency room visit, self-pay$1,200–$2,500+
Reviews
- 1 out of 5AnonymousJuly 28, 2026
Terrible experience, in reference to the nurse practitioner acting like a physician. Moody was his last name. On Saturday Went in for brown recluse bite on my arm. Expecting to get some type of treatment ie. steroids antibiotics. He claimed it barely bit me and I need to let it run its course. Told him I didn't want a big hole in my arm. Dr. Claimed it wouldn't happen. Went to my physician Monday, cause it was worse. She wanted to know why I hadn't gotten treatment sooner. She instantly gave me a shot, steroids and antibiotic. All I have now is a rotting black hole under my arm and a bill. He was uncaring and unprofessional.
Other urgent care centers in Sikeston
- Hours not listed · call to confirm1012 N Main St, Sikeston, MO 638010.1 mi from this listing
Missouri Delta Women’s Care Center
Hours not listed · call to confirm1013 N Main St, Sikeston, MO 638010.1 mi from this listingBarton-Jolly building
Hours not listed · call to confirm1019 N Main St, Sikeston, MO 638010.2 mi from this listingSmith Street Clinic
Hours listed · see hours123 Smith Ave, Sikeston, MO 638010.4 mi from this listingSikeston Urgent Care
Hours not listed · call to confirm918 S Kingshighway, Sikeston, MO 638011.5 mi from this listingVA Sikeston Clinic
Hours listed · see hours903 S Kingshighway, Sikeston, MO 638011.5 mi from this listing
Questions
Express Care is located at 1008 N Main St, Sikeston, MO 63801.
You can reach Express Care at (573) 472-6001.
Express Care is listed with Aetna. Please call to verify your specific plan.
Monday: 8:00 AM – 7:00 PM; Tuesday: 8:00 AM – 7:00 PM; Wednesday: 8:00 AM – 7:00 PM; Thursday: 8:00 AM – 7:00 PM; Friday: 8:00 AM – 7:00 PM; Saturday: 8:00 AM – 4:00 PM; Sunday: 8:00 AM – 4:00 PM. Please verify hours directly with the facility.
No, based on the hours we list: open weekdays 8 AM to 7 PM and weekends 8 AM to 4 PM. Please call to confirm.
Please contact Express Care directly to confirm walk-in availability.
Nearby cities
The information on this page is general information, not medical advice. Please verify hours, insurance and services directly with Express Care before visiting. In a medical emergency, call 911.